Question:
I took predinsone tablets. Five days after taking them my face started to swell. How long till the puffy face goes away? It has been like this for 8 days now. I am drinking about 1/2 gallan of distilled water every day to help flush out my system. Took 4 benadryl tablets today for the first time. so far no changes

Answer:
Some people get really fast the side effects of prednisone such as puffy face. Water won't help it and neither will benadryl. It usually goes away (often weeks to months) after stopping prednisone.