Question:
I am a 43 year old woman who was diagnosed with sjogrens 10 years ago.I have been taking 200mg of plaquenil twice daily since.I have always had numbness and tingling in arms,legs and the face but am now experiencing twitching and burning?cold sensation in legs/face.Could this be a sjogrens symptom?The twitching seems more pronounced when my legs are at rest.Would appreciate your thoughts on this.

Answer:
Sjogrens can cause a pure sensory neuropathy that you may be describing and it could get worse possibly causing the new symptoms. I am uncertain though what would be causing the twitching. Please discuss further with your doctor